Morphological and Bactericidal Effects of Amikacin, Meropenem and Imipenem on Pseudomonas aeruginosa
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منابع مشابه
Morphological and Bactericidal Effects of Amikacin, Meropenem and Imipenem on Pseudomonas aeruginosa
BACKGROUND Pseudomonas aeruginosa might be converted to coccoid bacteria under antibiotic stress. Bacterial conversion would increase resistance to antibiotics due to changes in cell wall crosslink or decreased metabolic activity. Morphology of P. aeruginosa under stress conditions (presence of antibiotics) can be changed to elongated bacilli, U shape and finally coccoid bacteria. Results of se...
متن کاملmorphological and bactericidal effects of amikacin, meropenem and imipenem on pseudomonas aeruginosa
conclusions induction of coccoid form of p. aeruginosa may be one of the important reasons for antibiotic treatment failure; therefore, prescribed dose of antibiotics should be carefully managed to prevent increasing antibiotic resistance and coccoid bacteria induction. results all used antibiotics at sub mic concentration had capability to induce coccoid bacteria. the highest rate of induced c...
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Serum bactericidal activity against 20 strains of Pseudomonas aeruginosa was studied in 10 volunteers after administration of imipenem (25 mg/kg), imipenem (25 mg/kg) plus amikacin (7.5 mg/kg), and ceftazidime (25 mg/kg) plus amikacin (7.5 mg/kg). Eight strains were susceptible and 12 were resistant to ticarcillin. Serum levels were measured microbiologically after 30 and 60 min and were, respe...
متن کاملThe Inhibitory Effect of Zinc on Imipenem and Meropenem Susceptibility of Pseudomonas aeruginosa
393 Abstract: In this study we have showed that zinc ion has an inhibitory activity on imipenem and meropenem suspectibility of Pseudomonas aeruginosa. When zinc ion concentration of Mueller-Hinthon agar (MHA) media was gradually increased the zone diameters of imipenem and meropenem gradually decreased. So we concluded that zinc concentration in the media might effect imipenem and meropenem su...
متن کاملPseudomonas aeruginosa carbapenem resistance mechanisms in Spain: impact on the activity of imipenem, meropenem and doripenem.
OBJECTIVES To investigate the mechanisms of carbapenem resistance in the 175 Pseudomonas aeruginosa isolates (39%; 175/448) showing non-susceptibility (European Committee on Antimicrobial Susceptibility Testing breakpoints) to imipenem (35%), meropenem (33%) and/or doripenem (33%) recovered in 2008-09 from 16 Spanish hospitals during the Comparative Activity of Carbapenem Testing (COMPACT) surv...
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ژورنال
عنوان ژورنال: Jundishapur Journal of Microbiology
سال: 2015
ISSN: 2008-3645,2008-4161
DOI: 10.5812/jjm.25250